产品详情
SNIPER(ABL)-058, conjugating Imatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 8.69 mL | 43.46 mL | 86.93 mL |
0.5 mM | 1.74 mL | 8.69 mL | 17.39 mL |
1 mM | 0.87 mL | 4.35 mL | 8.69 mL |
5 mM | 0.17 mL | 0.87 mL | 1.74 mL |
*The above data is based on the productmolecular weight 1150.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A19616 |
---|---|
M. Wt | 1150.39 |
Formula | C62H75N11O9S |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 2222354-61-0 |
SMILES | CC1=CC=C(NC(C2=CC=C(CN3CCN(C(COCCOCCOCCOC4=CC(C(C5=CSC([C@H]6N(C([C@H](C7CCCCC7)NC([C@H](C)NC)=O)=O)CCC6)=N5)=O)=CC=C4)=O)CC3)C=C2)=O)C=C1NC8=NC=CC(C9=CC=CN=C9)=N8 |
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