SNX-2112

目录号: A11189

Hsp90 inhibitor

SNX-2112 Chemical Structure

CAS NO. 908112-43-6

SNX-2112 is a heat shock protein 90 (Hsp90) inhibitor with anticancer properties currently in clinical trials. SNX-2112 induced autophagy in a time- and dose-dependent manner via Akt/mTOR/p70S6K inhibition. SNX-2112 induces significant apoptosis and autophagy in human melanoma A-375 cells, and may be an effective targeted therapy agent

库存: 现货

规格 价格 数量
5 mg
¥ 1,500.00
10 mg
¥ 2,200.00
50 mg
¥ 5,500.00
100 mg
¥ 9,200.00
10mM * 1mL in DMSO
¥ 1,980.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

SNX-2112 is a heat shock protein 90 (Hsp90) inhibitor with anticancer properties currently in clinical trials. SNX-2112 induced autophagy in a time- and dose-dependent manner via Akt/mTOR/p70S6K inhibition. SNX-2112 induces significant apoptosis and autophagy in human melanoma A-375 cells, and may be an effective targeted therapy agent

Targets
HSP90α HSP90β
30 nM(Ka)30 nM(Ka)
In vitro (25°C) DMSO 93 mg/mL (200.22 mM)
Water <1 mg/mL (<1 mM)
Ethanol 1 mg/mL (2.15 mM)
In vivo 0.5% CMC/0.25% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.53 mL 107.65 mL 215.29 mL
0.5 mM 4.31 mL 21.53 mL 43.06 mL
1 mM 2.15 mL 10.76 mL 21.53 mL
5 mM 0.43 mL 2.15 mL 4.31 mL

*The above data is based on the productmolecular weight 464.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11189
MECHANISM OF ACTION Inhibitor
M. Wt 464.48
Formula C23H27F3N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 908112-43-6
Synonyms SNX2112, PF 04928473
SMILES CC1(CC2=C(C(=O)C1)C(=NN2C3=CC(=C(C=C3)C(=O)N)NC4CCC(CC4)O)C(F)(F)F)C

产品标签

产品标签

其他人对该产品使用了下列标签:

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 SNX-2112 | SNX-2112 供应商 | 订购 SNX-2112 | SNX-2112 价格 | SNX-2112 生产商 | 订单 SNX-2112 | SNX-2112 代理商 | 购买 908112-43-6| 908112-43-6 供应商 | 订购 908112-43-6 | 908112-43-6 价格 | 908112-43-6 生产商 | 订单 908112-43-6 | 908112-43-6 代理商|buy SNX-2112 | SNX-2112 Supplier | purchase SNX-2112 | SNX-2112 cost | SNX-2112 manufacturer | order SNX-2112 | SNX-2112 distributor | buy 908112-43-6| 908112-43-6 Supplier | purchase 908112-43-6 | 908112-43-6 cost | 908112-43-6 manufacturer | order 908112-43-6 | 908112-43-6 distributor
Rewards