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Sofosbuvir impurity A, an diastereoisomer of sofosbuvir, is the impurity of sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.89 mL | 94.44 mL | 188.88 mL |
| 0.5 mM | 3.78 mL | 18.89 mL | 37.78 mL |
| 1 mM | 1.89 mL | 9.44 mL | 18.89 mL |
| 5 mM | 0.38 mL | 1.89 mL | 3.78 mL |
*The above data is based on the productmolecular weight 529.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21641 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 529.45 |
| Formula | C22H29FN3O9P |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1496552-16-9 |
| SMILES | O=[P@](N[C@H](C)C(OC(C)C)=O)(OC[C@@H]1[C@@H](O)[C@](F)(C)[C@H](N2C=CC(NC2=O)=O)O1)OC3=CC=CC=C3 |
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