Solitomab (AMG 110) is a bispecific antibody designed to target both CD3, a T-cell co-receptor, and Epithelial Cell Adhesion Molecule (EpCAM), which is frequently overexpressed in various carcinomas. This dual targeting mechanism facilitates the redirection of T cells to EpCAM-expressing tumor cells, promoting T-cell mediated cytotoxicity. Solitomab is primarily utilized in research focused on primary uterine and ovarian carcinosarcoma, providing a valuable tool for investigating the therapeutic potential of bispecific antibodies in cancer immunotherapy.
Solitomab (AMG 110) is a bispecific antibody designed to target both CD3, a T-cell co-receptor, and Epithelial Cell Adhesion Molecule (EpCAM), which is frequently overexpressed in various carcinomas. This dual targeting mechanism facilitates the redirection of T cells to EpCAM-expressing tumor cells, promoting T-cell mediated cytotoxicity. Solitomab is primarily utilized in research focused on primary uterine and ovarian carcinosarcoma, providing a valuable tool for investigating the therapeutic potential of bispecific antibodies in cancer immunotherapy.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
