Sophocarpine
目录号: A10857
苦参碱能够逆转异丙肾上腺素引起的心律失常，并抑制 I(Na)、I(CaL) 和 I(Kr) 电流。苦参碱的电生理效应与胺碘酮相似，可能被视为一种潜在的抗心律失常药物。
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生物活性
| Discription | Sophocarpine could reverse isoprenaline-induced arrhythmia and inhibit I(Na), I(CaL), and I(Kr) currents. The electrophysiological effects of sophocarpine are similar to those of amiodarone, which might be regarded as a prospective antiarrhythmic agent. | |||||
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产品信息
| 目录号 | A10857 |
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| 分子式 | C15H22N2O |
| 分子量 | 246.4 |
| CAS号 | 6483-15-4 |
| SMILES | C1C[C@H]2CN3[C@H](CC=CC3=O)[C@@H]4[C@H]2N(C1)CCC4 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 47 mg/mL (190.78 mM) | |
| Water | 6 mg/mL (24.35 mM) | ||
| Ethanol | 47 mg/mL (190.78 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 40.58 mL | 202.92 mL | 405.84 mL |
| 0.5 mM | 8.12 mL | 40.58 mL | 81.17 mL |
| 1 mM | 4.06 mL | 20.29 mL | 40.58 mL |
| 5 mM | 0.81 mL | 4.06 mL | 8.12 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 6483-15-4 | 6483-15-4 供应商 | 6483-15-4 花费 | 6483-15-4 生产商 | 订购 6483-15-4 | 6483-15-4 代理商