Sotrastaurin (AEB071)

目录号: A11554

PKC inhibitor

Sotrastaurin (AEB071)

Sotrastaurin (AEB071) Chemical Structure

CAS NO. 425637-18-9

Sotrastaurin is a protein kinase C inhibitor for the prevention of transplant rejection and treatment of psoriasis.

库存: 现货

规格 价格 数量
5 mg
¥ 1,200.00
10 mg
¥ 2,000.00
25 mg
¥ 3,800.00
50 mg
¥ 6,200.00
10mM * 1mL in DMSO
¥ 1,640.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Sotrastaurin is a protein kinase C inhibitor for the prevention of transplant rejection and treatment of psoriasis.
Targets
Target Value
PKCθki: 0.22nM
PKCβ1ki: 0.64nM
PKCαki: 0.95nM
PKCηki: 1.8nM
PKCδki: 2.1nM
PKCεki: 3.2nM
In vitro DMSO 87 mg/mL (198.41 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (4.56 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.81 mL 114.03 mL 228.05 mL
0.5 mM 4.56 mL 22.81 mL 45.61 mL
1 mM 2.28 mL 11.4 mL 22.81 mL
5 mM 0.46 mL 2.28 mL 4.56 mL

*The above data is based on the productmolecular weight 438.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11554
MECHANISM OF ACTION Inhibitor
M. Wt 438.5
Formula C25H22N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 425637-18-9
Synonyms AEB 071, AEB-071
SMILES CN1CCN(CC1)C2=NC3=CC=CC=C3C(=N2)C4=C(C(=O)NC4=O)C5=CNC6=CC=CC=C65

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