Spartalizumab (PDR001) is a humanized IgG4 monoclonal antibody designed to bind to programmed death-1 (PD-1) receptor with subnanomolar affinity. By inhibiting the interaction between PD-1 and its ligands PD-L1 and PD-L2, Spartalizumab effectively modulates immune responses. This antibody is primarily utilized in research focused on anaplastic thyroid carcinoma (ATC), providing a valuable tool for investigating immune checkpoint pathways in cancer immunotherapy studies.
Spartalizumab (PDR001) is a humanized IgG4 monoclonal antibody designed to bind to programmed death-1 (PD-1) receptor with subnanomolar affinity. By inhibiting the interaction between PD-1 and its ligands PD-L1 and PD-L2, Spartalizumab effectively modulates immune responses. This antibody is primarily utilized in research focused on anaplastic thyroid carcinoma (ATC), providing a valuable tool for investigating immune checkpoint pathways in cancer immunotherapy studies.
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