Spastazoline

Name: Spastazoline
SKU: A19432
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A19432

spastin 抑制剂

Spastazoline 是一种强效且选择性的 spastin（一种切割微管的 AAA 蛋白）抑制剂，对人类 spastin 的 IC50 为 99 nM。Spastazoline 对重组人类 VPS4 的 ATPase 活性没有影响。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥420.00	现货
10mg	¥735.00	现货
25mg	¥1,540.00	现货
50mg	¥2,345.00	现货
100mg	¥3,360.00	现货
200mg	¥4,690.00	现货
*10mM 1mL in DMSO**	¥490.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription	Spastazoline is a potent and selective spastin (a microtubule-severing AAA protein) inhibitor, with an IC50 of 99 nM for Human spastin. Spastazoline shows no effect on ATPase activity of a recombinant human VPS4.

产品信息

目录号	A19432
分子式	C20H30N8
分子量	382.51
CAS号	2351882-11-4
SMILES	CC(C)(C)C1=CC(NC2=NC(N3CCN[C@H](C(C)C)C3)=NC4=C2C=CN4)=NN1
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	69 mg/mL (180.38 mM)
	Water	Insoluble
	Ethanol	18 mg/mL (47.05 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.14 mL	130.72 mL	261.43 mL
0.5 mM	5.23 mL	26.14 mL	52.29 mL
1 mM	2.61 mL	13.07 mL	26.14 mL
5 mM	0.52 mL	2.61 mL	5.23 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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