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SPDB-DM4 is a drug-linker conjugate for ADC by using the maytansinebased payload (DM4, a tubulin inhibitor) via a SPDB linker, exhibiting potent anti-tumor activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 10.04 mL | 50.22 mL | 100.44 mL |
| 0.5 mM | 2.01 mL | 10.04 mL | 20.09 mL |
| 1 mM | 1 mL | 5.02 mL | 10.04 mL |
| 5 mM | 0.2 mL | 1 mL | 2.01 mL |
*The above data is based on the productmolecular weight 995.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21413 |
|---|---|
| M. Wt | 995.59 |
| Formula | C46H63ClN4O14S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1626359-62-3 |
| SMILES | C[C@]1([C@H](CC(N(C(C=C2C=C3OC)=C3Cl)C)=O)OC([C@H](C)N(C)C(CCC(C)(C)SSCCCC(ON(C4=O)C(CC4)=O)=O)=O)=O)[C@H]([C@@H]([C@](OC5=O)([H])C[C@]([C@](/C=C/C=C(C)/C2)([H])OC)(N5)O)C)O1 |
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