Splitomicin
目录号: A14221
NAD(+)-dependent histone deacetylase Sir2p 抑制剂
Splitomicin 是一种选择性的 NAD(+)-依赖型组蛋白去乙酰化酶 Sir2p 抑制剂,其 IC50 为 60 uM,在基于细胞的实验中显示出更高的活性。
| Discription | Splitomicin is a selective NAD(+)-dependent histone deacetylase Sir2p inhibitor with IC50 of 60 uM, showing a higher activity in a cell-based assay. | ||
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| Targets |
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| 目录号 | A14221 |
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| 分子式 | C13H10O2 |
| 分子量 | 198.22 |
| CAS号 | CAS: 5690-03-9 |
| SMILES | C1CC(=O)OC2=C1C3=CC=CC=C3C=C2 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 37 mg/mL (186.66 mM) | |
| Water | Insoluble | ||
| Ethanol | 37 mg/mL (186.66 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 50.45 mL | 252.24 mL | 504.49 mL |
| 0.5 mM | 10.09 mL | 50.45 mL | 100.9 mL |
| 1 mM | 5.04 mL | 25.22 mL | 50.45 mL |
| 5 mM | 1.01 mL | 5.04 mL | 10.09 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2