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SR 3576是一种高效的选择性JNK3抑制剂（IC50 = 7 nM）；表现出比p38高2800倍的选择性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.94 mL | 99.69 mL | 199.39 mL |
| 0.5 mM | 3.99 mL | 19.94 mL | 39.88 mL |
| 1 mM | 1.99 mL | 9.97 mL | 19.94 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.99 mL |
*The above data is based on the productmolecular weight 501.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16020 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 501.53 |
| Formula | C27H27N5O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1164153-22-3 |
| Synonyms | JNK3 Inhibitor XII, SR-3576, SR3576 |
| SMILES | O=C(C1=CC(N2N=CC(NC(NC3=CC=CC(C)=C3)=O)=C2)=CC=C1)NC(C=C4OC)=CC(OC)=C4OC |
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