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SR 3677 dihydrochloride是一种有效的选择性Rho激酶抑制剂（ROCK-II和ROCK-I的IC50值分别为3和56 nM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.77 mL | 103.87 mL | 207.74 mL |
| 0.5 mM | 4.15 mL | 20.77 mL | 41.55 mL |
| 1 mM | 2.08 mL | 10.39 mL | 20.77 mL |
| 5 mM | 0.42 mL | 2.08 mL | 4.15 mL |
*The above data is based on the productmolecular weight 481.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12674 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 481.37 |
| Formula | C22H24N4O4.2HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1072959-67-1 |
| Synonyms | SR3677, SR-3677 |
| SMILES | CN(C)CCOC1=C(C=CC(=C1)C2=CNN=C2)NC(=O)C3COC4=CC=CC=C4O3 |
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