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SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 (CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.03 mL | 100.13 mL | 200.26 mL |
| 0.5 mM | 4.01 mL | 20.03 mL | 40.05 mL |
| 1 mM | 2 mL | 10.01 mL | 20.03 mL |
| 5 mM | 0.4 mL | 2 mL | 4.01 mL |
*The above data is based on the productmolecular weight 499.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22337 |
|---|---|
| M. Wt | 499.36 |
| Formula | C21H20Cl2N10O |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 2387704-62-1 |
| Synonyms | SR4835,SR 4835 |
| SMILES | CN1N=CC(N2C3=NC(N4CCOCC4)=NC(NCC5=NC6=C(N5)C=C(Cl)C(Cl)=C6)=C3N=C2)=C1 |
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