SRT 1460
目录号: A19026
SIRT1 activator
SRT 1460 是一种强效的 Sirtuin-1 (SIRT1) 激活剂，其 EC1.5 值为 2.9 微摩尔，显示出对 SIRT1 与 SIRT2 和 SIRT3 的良好选择性（EC1.5>300 微摩尔），并且比白藜芦醇和最接近的 sirtuin 同源物更为强效。
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生物活性
| Discription | SRT 1460, a potent Sirtuin-1 (SIRT1) activator with an EC1.5 value of 2.9 μM, shows good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 μM), and is more potent than Resveratrol and the closest sirtuin homologues. | ||
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产品信息
| 目录号 | A19026 |
|---|---|
| 分子式 | C26H29N5O4S |
| 分子量 | 507.6 |
| CAS号 | 925432-73-1 |
| SMILES | O=C(NC1=CC=CC=C1C2=CN3C(SC=C3CN4CCNCC4)=N2)C5=CC(OC)=C(OC)C(OC)=C5 |
| 其他名称 | SRT-1460, SRT1460 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 20 mg/mL (39.4 mM) | |
| Water | Insoluble | ||
| Ethanol | 1 mg/mL (1.97 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.7 mL | 98.5 mL | 197.01 mL |
| 0.5 mM | 3.94 mL | 19.7 mL | 39.4 mL |
| 1 mM | 1.97 mL | 9.85 mL | 19.7 mL |
| 5 mM | 0.39 mL | 1.97 mL | 3.94 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 925432-73-1 | 925432-73-1 供应商 | 925432-73-1 花费 | 925432-73-1 生产商 | 订购 925432-73-1 | 925432-73-1 代理商