SRT 1460

目录号: A19026

SIRT1 activator

SRT 1460

SRT 1460 Chemical Structure

CAS NO. 925432-73-1

SRT 1460, a potent Sirtuin-1 (SIRT1) activator with an EC1.5 value of 2.9 μM, shows good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 μM), and is more potent than Resveratrol and the closest sirtuin homologues.

库存: 现货

规格 价格 数量
5 mg
¥ 3,500.00
10 mg
¥ 6,500.00
50 mg
¥ 20,000.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

SRT 1460, a potent Sirtuin-1 (SIRT1) activator with an EC1.5 value of 2.9 μM, shows good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 μM), and is more potent than Resveratrol and the closest sirtuin homologues.
In vitro DMSO 20 mg/mL (39.4 mM)
Water Insoluble
Ethanol 1 mg/mL (1.97 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.7 mL 98.5 mL 197.01 mL
0.5 mM 3.94 mL 19.7 mL 39.4 mL
1 mM 1.97 mL 9.85 mL 19.7 mL
5 mM 0.39 mL 1.97 mL 3.94 mL

*The above data is based on the productmolecular weight 507.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A19026
作用机制 Activator (激活剂)
M. Wt 507.6
Formula C26H29N5O4S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 925432-73-1
Synonyms SRT-1460, SRT1460
SMILES O=C(NC1=CC=CC=C1C2=CN3C(SC=C3CN4CCNCC4)=N2)C5=CC(OC)=C(OC)C(OC)=C5

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