SRT 2183

Name: SRT 2183
SKU: A12150

目录号: A12150

Sirtuin-1 (SIRT1) activator

SRT 2183 Chemical Structure

CAS NO. 1001908-89-9

SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM. SRT 2183 induces growth arrest and apoptosis, concomitant with deacetylation of STAT3 and NF-κB, and reduction of c-Myc protein levels.

库存：现货

规格	价格	数量
5 mg	￥ 1,220.00
10 mg	￥ 2,090.00
50 mg	￥ 6,210.00

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生物活性

溶解度 *

In vitro	DMSO	86 mg/mL (183.53 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (6.4 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.34 mL	106.71 mL	213.42 mL
0.5 mM	4.27 mL	21.34 mL	42.68 mL
1 mM	2.13 mL	10.67 mL	21.34 mL
5 mM	0.43 mL	2.13 mL	4.27 mL

*The above data is based on the productmolecular weight 468.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12150
作用机制	Activator (激活剂)
M. Wt	468.57
Formula	C27H24N4O2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1001908-89-9
Synonyms	SRT2183, SRT-2183
SMILES	O=C(NC1=C(C2=CN3C(SC=C3CN4CC[C@@H](O)C4)=N2)C=CC=C1)C(C=C5)=CC6=C5C=CC=C6