SRT 2183

Name: SRT 2183
SKU: A12150
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A12150

Sirtuin-1 (SIRT1) activator

SRT 2183 是一种选择性的Sirtuin-1 (SIRT1) 激活剂，其 EC1.5 值为 0.36 微摩尔。SRT 2183 诱导生长停滞和凋亡，同时伴随 STAT3 和 NF-κB 的去乙酰化，以及 c-Myc 蛋白水平的降低。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥420.00	现货
5mg	¥700.00	现货
10mg	¥1,120.00	现货
25mg	¥2,030.00	现货
50mg	¥3,115.00	现货
100mg	¥4,550.00	现货
*10mM 1mL in DMSO**	¥735.00	现货
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Data Sheet

SDS

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生物活性

Discription

SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM. SRT 2183 induces growth arrest and apoptosis, concomitant with deacetylation of STAT3 and NF-κB, and reduction of c-Myc protein levels.

Targets

Target	Value

产品信息

目录号	A12150
分子式	C27H24N4O2S
分子量	468.57
CAS号	1001908-89-9
SMILES	O=C(NC1=C(C2=CN3C(SC=C3CN4CC[C@@H](O)C4)=N2)C=CC=C1)C(C=C5)=CC6=C5C=CC=C6
其他名称	SRT2183, SRT-2183
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	86 mg/mL (183.53 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (6.4 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.34 mL	106.71 mL	213.42 mL
0.5 mM	4.27 mL	21.34 mL	42.68 mL
1 mM	2.13 mL	10.67 mL	21.34 mL
5 mM	0.43 mL	2.13 mL	4.27 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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