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SRT1720 HCl是一种抑制剂，旨在作为瑟土因亚型SIRT1的小分子活化剂。
靶点信息
| SIRT1 (Cell-free assay) | ||||
| 0.16 μM(EC50) |
| In vitro | DMSO | 34 mg/mL (67.19 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.76 mL | 98.81 mL | 197.63 mL |
| 0.5 mM | 3.95 mL | 19.76 mL | 39.53 mL |
| 1 mM | 1.98 mL | 9.88 mL | 19.76 mL |
| 5 mM | 0.4 mL | 1.98 mL | 3.95 mL |
*The above data is based on the productmolecular weight 506.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10862 |
|---|---|
| 作用机制 | Activator (激活剂) |
| M. Wt | 506.0 |
| Formula | C25H23N7OS.HCl |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1001645-58-4 |
| Synonyms | SRT-1720 |
| SMILES | C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl |
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