STA-21
目录号: A15885
STAT-3 抑制剂
STA-21 是一种有前景的 STAT-3 抑制剂,它可以相互调节 Th17 和 Treg 细胞,在小鼠和人类中抑制 成骨细胞生成,并在类风湿性关节炎的实验模型中缓解自身免疫炎症。
Discription | STA-21 is a promising STAT-3 inhibitor that reciprocally regulates Th17 and Treg cells, inhibits osteoclastogenesis in mice and humans and alleviates autoimmune inflammation in an experimental model of rheumatoid arthritis. | ||
---|---|---|---|
Targets |
|
目录号 | A15885 |
---|---|
分子式 | C19H14O4 |
分子量 | 306.31 |
CAS号 | 111540-00-2 |
SMILES | O=C1CC(C)CC2=CC=C3C(C(C4=CC=CC(O)=C4C3=O)=O)=C12 |
其他名称 | Ochromycinone |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 21 mg/mL (68.55 mM) | |
Water | Insoluble | ||
Ethanol | 2 mg/mL (6.52 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 32.65 mL | 163.23 mL | 326.47 mL |
0.5 mM | 6.53 mL | 32.65 mL | 65.29 mL |
1 mM | 3.26 mL | 16.32 mL | 32.65 mL |
5 mM | 0.65 mL | 3.26 mL | 6.53 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2