STAT3-IN-1

Name: STAT3-IN-1
SKU: A12232
Price: 350 CNY
Rating: 5 (2 reviews)

目录号: A12232

STAT3 抑制剂

2 篇发表文献

STAT3-IN-1（化合物7d）是一种优秀的、选择性的、口服活性的 STAT3 抑制剂，在 HT29 和 MDA-MB 231 细胞中的 IC50 值分别为 1.82 μM 和 2.14 μM。STAT3-IN-1（化合物7d）能诱导肿瘤细胞凋亡。

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Grouped product items
规格	价格	库存
1mg	¥350.00	现货
2mg	¥525.00	现货
5mg	¥875.00	现货
10mg	¥1,365.00	现货
25mg	¥2,520.00	现货
50mg	¥3,815.00	现货
100mg	¥5,495.00	现货
500mg	¥11,375.00	现货
*10mM 1mL in DMSO**	¥910.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用STAT3-IN-1发表的2篇文献

Majid Momeny, .et al. , EMBO Mol Med, 2024, Jun 17 PMID: 38886591

Rongshou Wu, .et al. , Sci Rep, 2023, 13: 16998 PMID: 37813900

生物活性

Discription

STAT3-IN-1 (compound 7d) is an excellent, selective and orally active STAT3 inhibitor, with IC50 values of 1.82 μM and 2.14 μM in HT29 and MDA-MB 231 cells, respectively. STAT3-IN-1 (compound 7d) induces tumor apoptosis.

Targets

Target	Value

产品信息

目录号	A12232
分子式	C28H29NO6
分子量	475.53
CAS号	2059952-75-7
SMILES	COC1=CC(OC)=CC(/C=C/C2=CC=C(NC(/C=C/C3=CC(OC)=C(OC)C(OC)=C3)=O)C=C2)=C1
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	81 mg/mL (170.33 mM)
	Water	Insoluble
	Ethanol	4 mg/mL (8.41 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.03 mL	105.15 mL	210.29 mL
0.5 mM	4.21 mL	21.03 mL	42.06 mL
1 mM	2.1 mL	10.51 mL	21.03 mL
5 mM	0.42 mL	2.1 mL	4.21 mL

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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