Staurosporine

目录号: A10864

PKC inhibitor

Staurosporine Chemical Structure

CAS NO. 62996-74-1

Staurosporine is a natural product originally isolated in 1977 from the bacterium Streptomyces staurosporeus. The main biological activity of staurosporine is the inhibition of protein kinases through the prevention of ATP binding to the kinase. This is achieved through the stronger affinity of staurosporine to the ATP-binding site on the kinase.

库存: 现货

规格 价格 数量
5 mg
¥ 1,100.00
10 mg
¥ 1,500.00
25 mg
¥ 3,000.00
50 mg
¥ 5,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

Staurosporine is a natural product originally isolated in 1977 from the bacterium Streptomyces staurosporeus. The main biological activity of staurosporine is the inhibition of protein kinases through the prevention of ATP binding to the kinase. This is achieved through the stronger affinity of staurosporine to the ATP-binding site on the kinase.
Targets
Target Value
PKCαIC50: 2nM
c-FgrIC50: 2nM
phosphorylasekinaseIC50: 3nM
PKCηIC50: 4nM
PKCγIC50: 5nM
S6kinaseIC50: 5nM
v-SrcIC50: 6nM
Cdc2IC50: 9nM
Cdc2IC50: 9nM
PKAIC50: 15nM
SykIC50: 16nM
PKGIC50: 18nM
PKCδIC50: 20nM
CaMKIIIC50: 20nM
LynIC50: 20nM
MLCKIC50: 21nM
PKCεIC50: 73nM
PKCζIC50: 1086nM
In vitro DMSO 4 mg/mL (8.57 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.44 mL 107.18 mL 214.36 mL
0.5 mM 4.29 mL 21.44 mL 42.87 mL
1 mM 2.14 mL 10.72 mL 21.44 mL
5 mM 0.43 mL 2.14 mL 4.29 mL

*The above data is based on the productmolecular weight 466.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10864
MECHANISM OF ACTION Inhibitor
M. Wt 466.5
Formula C28H26N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 62996-74-1
Synonyms AM-2282, STS
SMILES C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC

产品标签

产品标签

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 Staurosporine | Staurosporine 供应商 | 订购 Staurosporine | Staurosporine 价格 | Staurosporine 生产商 | 订单 Staurosporine | Staurosporine 代理商 | 购买 62996-74-1| 62996-74-1 供应商 | 订购 62996-74-1 | 62996-74-1 价格 | 62996-74-1 生产商 | 订单 62996-74-1 | 62996-74-1 代理商|buy Staurosporine | Staurosporine Supplier | purchase Staurosporine | Staurosporine cost | Staurosporine manufacturer | order Staurosporine | Staurosporine distributor | buy 62996-74-1| 62996-74-1 Supplier | purchase 62996-74-1 | 62996-74-1 cost | 62996-74-1 manufacturer | order 62996-74-1 | 62996-74-1 distributor
Rewards