Staurosporine

Name: Staurosporine
SKU: A10864
Price: 350 CNY
Rating: 5 (3 reviews)

目录号: A10864

PKC 抑制剂

3 篇发表文献

Staurosporine 是一种天然产物，最初于 1977 年从细菌 Streptomyces staurosporeus 中分离出来。Staurosporine 的主要生物活性是通过阻止 ATP 与激酶结合来抑制 蛋白激酶。这是通过 Staurosporine 对激酶上的 ATP 结合位点具有更强的亲和力来实现的。

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Grouped product items
规格	价格	库存
1mg	¥350.00	现货
2mg	¥490.00	现货
5mg	¥630.00	现货
10mg	¥980.00	现货
25mg	¥1,750.00	现货
50mg	¥2,905.00	现货
100mg	¥4,340.00	现货
500mg	¥9,415.00	现货
*10mM 1mL in DMSO**	¥735.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Staurosporine发表的3篇文献

Lisa M Kim, .et al. , Cancer Res, 2022, Sep 2;82(17):3045-3057 PMID: 35792658

Jacobs CL, .et al. , Nat Methods, 2018, Jul;15(7):523-526 PMID: 29967496

Birte Plitzko, .et al. , J Biol Chem, 2017, Dec 22; 292(51): 21102-21116 PMID: 29074620

生物活性

Discription

Staurosporine is a natural product originally isolated in 1977 from the bacterium Streptomyces staurosporeus. The main biological activity of staurosporine is the inhibition of protein kinases through the prevention of ATP binding to the kinase. This is achieved through the stronger affinity of staurosporine to the ATP-binding site on the kinase.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10864
分子式	C28H26N4O3
分子量	466.5
CAS号	62996-74-1
SMILES	C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
其他名称	AM-2282, STS
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	4 mg/mL (8.57 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.44 mL	107.18 mL	214.36 mL
0.5 mM	4.29 mL	21.44 mL	42.87 mL
1 mM	2.14 mL	10.72 mL	21.44 mL
5 mM	0.43 mL	2.14 mL	4.29 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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