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STF 118804

NAMPT 抑制剂

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产品目录号: A14072

库存状态:中国现货中国现货

产品名 目录号 价格 数量
STF 118804 10mg A14072-10
¥ 1,100.00
STF 118804 25mg A14072-25
¥ 2,200.00
STF 118804 50mg A14072-50
¥ 3,800.00
STF 118804 10mM * 1mL in DMSO A14072-10mM-D
¥ 850.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

STF 118804 is a highly specific NAMPT inhibitor that reduces the viability of most B-ALL cell lines with high potency IC50 values in the low nanomolar range and improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia.

STF 118804

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Chemical Information

目录号 A14072
Mechanism of action Inhibitor
分子量 461.53
化学分子式 C25H23N3O4S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 894187-61-2
Synonyms STF118804, STF-118804
SMILES code CC1=CC=C(C=C1)S(=O)(=O)CC2=C(OC(=N2)C3=CC=C(C=C3)C(=O)NCC4=CN=CC=C4)C
化学名称 4-(5-Methyl-4-(tosylmethyl)oxazol-2-yl)-N-(pyridin-3-ylmethyl)benzamide

生物活性

Description
STF 118804 is a highly specific NAMPT inhibitor that reduces the viability of most B-ALL cell lines with high potency IC50 values in the low nanomolar range and improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia.
Targets
NAMPT

溶解性

Solubility (25°C)* In vitro DMSO 61 mg/mL (132.16 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.67 mL 108.34 mL 216.67mL
0.5 mM 4.33 mL 21.67 mL 43.33 mL
1 mM 2.17 mL 10.83 mL 21.67 mL
5 mM 0.43 mL 2.17 mL 4.33 mL

*The above data is based on the productmolecular weight 461.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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