STF-62247

目录号: A10866

Autophagy Inducer

STF-62247 Chemical Structure

CAS NO. 315702-99-9

STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM).

库存: 现货

规格 价格 数量
10 mg
¥ 500.00
25 mg
¥ 1,100.00
50 mg
¥ 1,900.00
100 mg
¥ 3,500.00
10mM * 1mL in DMSO
¥ 500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM).
Targets
In vitro (25°C) DMSO 53 mg/mL (198.24 mM)
Water <1 mg/mL (<1 mM)
Ethanol 3 mg/mL (11.22 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 7 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.4 mL 186.99 mL 373.97 mL
0.5 mM 7.48 mL 37.4 mL 74.79 mL
1 mM 3.74 mL 18.7 mL 37.4 mL
5 mM 0.75 mL 3.74 mL 7.48 mL

*The above data is based on the productmolecular weight 267.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10866
MECHANISM OF ACTION Inducer
M. Wt 267.4
Formula C15H13N3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 315702-99-9
Synonyms STF62247
SMILES CC1=CC(=CC=C1)NC2=NC(=CS2)C3=CC=NC=C3

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