STF-62247
目录号: A10866
Autophagy Inducer
STF-62247 是一种小分子激动剂，能够诱导自噬并选择性地对失去了 von Hippel-Lindau (VHL) 肿瘤抑制活性的肾细胞癌（RCC）细胞产生致死效果（IC50 = 625 nM）。
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生物活性
| Discription | STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM). | |||||
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| Cell Research |
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产品信息
| 目录号 | A10866 |
|---|---|
| 分子式 | C15H13N3S |
| 分子量 | 267.4 |
| CAS号 | 315702-99-9 |
| SMILES | CC1=CC(=CC=C1)NC2=NC(=CS2)C3=CC=NC=C3 |
| 其他名称 | STF62247 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 47 mg/mL (175.8 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (11.22 mM) | ||
| In vivo | 1% DMSO+30% polyethylene glycol+1% Tween 80 | 6 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37.4 mL | 186.99 mL | 373.97 mL |
| 0.5 mM | 7.48 mL | 37.4 mL | 74.79 mL |
| 1 mM | 3.74 mL | 18.7 mL | 37.4 mL |
| 5 mM | 0.75 mL | 3.74 mL | 7.48 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 315702-99-9 | 315702-99-9 供应商 | 315702-99-9 花费 | 315702-99-9 生产商 | 订购 315702-99-9 | 315702-99-9 代理商