SU-5402 Chemical Structure

CAS NO. 215543-92-3

SU-5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor (IC50 values are 0.02, 0.03, 0.51 and > 100 μM at VEGFR2, FGFR1, PDGFRβ and EGFR respectively).

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 1,000.00
25 mg
¥ 2,000.00
50 mg
¥ 3,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

SU-5402 is a potent and selective vascular endothelial growth factor receptor (VEGFR) and fibroblast growth factor receptor (FGFR) inhibitor (IC50 values are 0.02, 0.03, 0.51 and > 100 μM at VEGFR2, FGFR1, PDGFRβ and EGFR respectively).
Targets
VEGFR2 FGFR1 PDGFRβ
20 nM30 nM510 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.75 mL 168.74 mL 337.47 mL
0.5 mM 6.75 mL 33.75 mL 67.49 mL
1 mM 3.37 mL 16.87 mL 33.75 mL
5 mM 0.67 mL 3.37 mL 6.75 mL

*The above data is based on the productmolecular weight 296.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11558
MECHANISM OF ACTION Inhibitor
M. Wt 296.32
Formula C17H16N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 215543-92-3
Synonyms SU5402, SU 5402
SMILES CC1=CNC(=C1CCC(=O)O)/C=C\2/C3=CC=CC=C3NC2=O

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