SU11274

目录号: A10869

c-Met inhibitor

SU11274

SU11274 Chemical Structure

CAS NO. 658084-23-2

SU11274 is a Met tyrosine kinase inhibitor.

库存: 现货

规格 价格 数量
5 mg
¥ 600.00
10 mg
¥ 1,100.00
50 mg
¥ 4,800.00
100 mg
¥ 7,000.00
10mM * 1mL in DMSO
¥ 1,270.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

SU11274 is a Met tyrosine kinase inhibitor.
Targets
Target Value
MetIC50: 0.01μM
Flk1IC50: 1.25μM
RONIC50: 4.0μM
FGFR1IC50: 8.5μM
CDK2IC50: >10μM
PDGFRβIC50: >20μM
EGFRIC50: >100μM
In vitro (25°C) DMSO 92 mg/mL (161.94 mM)
Water <1 mg/mL (<1 mM)
Ethanol 2 mg/mL (3.52 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.6 mL 88.01 mL 176.03 mL
0.5 mM 3.52 mL 17.6 mL 35.21 mL
1 mM 1.76 mL 8.8 mL 17.6 mL
5 mM 0.35 mL 1.76 mL 3.52 mL

*The above data is based on the productmolecular weight 568.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10869
MECHANISM OF ACTION Inhibitor
M. Wt 568.1
Formula C28H30CIN5O4S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 658084-23-2
Synonyms SU-11274, PKI-SU11274
SMILES CC1=C(NC(=C1C(=O)N2CCN(CC2)C)C)/C=C\3/C4=C(C=CC(=C4)S(=O)(=O)N(C)C5=CC(=CC=C5)Cl)NC3=O

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