SU9516
目录号: A14318
CDK2 抑制剂
SU9516 是一种强效、选择性的 cdk2 抑制剂。它抑制 pRb 磷酸化，导致 pRB/E2F 复合体 形成增强，并诱导 G1 和 G2-M 细胞周期阻滞。
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生物活性
| Discription | SU9516 is a potent, selective cdk2 inhibitor. It inhibits pRb phosphorylation causing enhanced pRB/E2F complex formation and induces G1 and G2-M cell cycle arrest. | ||
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产品信息
| 目录号 | A14318 |
|---|---|
| 分子式 | C13H11N3O2 |
| 分子量 | 241.25 |
| CAS号 | 377090-84-1 |
| SMILES | COC1=CC\2=C(C=C1)NC(=O)/C2=C\C3=CN=CN3 |
| 其他名称 | SU 9516, SU-9516 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 44 mg/mL (182.38 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 11 mg/mL (45.6 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 41.45 mL | 207.25 mL | 414.51 mL |
| 0.5 mM | 8.29 mL | 41.45 mL | 82.9 mL |
| 1 mM | 4.15 mL | 20.73 mL | 41.45 mL |
| 5 mM | 0.83 mL | 4.15 mL | 8.29 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 377090-84-1 | 377090-84-1 供应商 | 377090-84-1 花费 | 377090-84-1 生产商 | 订购 377090-84-1 | 377090-84-1 代理商