Suvratoxumab (MEDI4893) is a high-affinity, long-acting human monoclonal antibody of the IgG1?? subtype, designed to target and neutralize ??-toxin, a critical virulence factor of Staphylococcus aureus. This antibody has demonstrated efficacy in enhancing survival rates and reducing pulmonary damage in immunocompromised mouse models of pneumonia. Additionally, Suvratoxumab has been shown to augment the antibacterial effects of antibiotics such as Vancomycin and Linezolid, suggesting its potential utility in synergistic therapeutic strategies against S. aureus infections.
Suvratoxumab (MEDI4893) is a high-affinity, long-acting human monoclonal antibody of the IgG1?? subtype, designed to target and neutralize ??-toxin, a critical virulence factor of Staphylococcus aureus. This antibody has demonstrated efficacy in enhancing survival rates and reducing pulmonary damage in immunocompromised mouse models of pneumonia. Additionally, Suvratoxumab has been shown to augment the antibacterial effects of antibiotics such as Vancomycin and Linezolid, suggesting its potential utility in synergistic therapeutic strategies against S. aureus infections.
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