SW033291
目录号: A15798
15-PGDH enzyme 抑制剂
SW033291 是一种小分子抑制剂,针对 15-PGDH(Ki=0.1 nM),能够增加骨髓和其他组织中前列腺素 PGE2 的水平。
Discription | SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues. | ||
---|---|---|---|
Targets |
|
目录号 | A15798 |
---|---|
分子式 | C21H20N2OS3 |
分子量 | 412.59 |
CAS号 | 459147-39-8 |
SMILES | NC1=C(S(CCCC)=O)SC2=NC(C3=CC=CS3)=CC(C4=CC=CC=C4)=C21 |
其他名称 | SW 033291, SW-033291 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 77 mg/mL (186.62 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 30 mg/mL (72.7 mM) | ||
In vivo | 5% DMSO+corn oil | 9 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.24 mL | 121.19 mL | 242.37 mL |
0.5 mM | 4.85 mL | 24.24 mL | 48.47 mL |
1 mM | 2.42 mL | 12.12 mL | 24.24 mL |
5 mM | 0.48 mL | 2.42 mL | 4.85 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2