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SYN1143 is a potent, selective and orally active dual inhibitor of c-Met/RON, with IC50s of 4 and 9 nM, respectively.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 17.97 mL | 89.83 mL | 179.67 mL |
0.5 mM | 3.59 mL | 17.97 mL | 35.93 mL |
1 mM | 1.8 mL | 8.98 mL | 17.97 mL |
5 mM | 0.36 mL | 1.8 mL | 3.59 mL |
*The above data is based on the productmolecular weight 556.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A22327 |
---|---|
M. Wt | 556.58 |
Formula | C31H29FN4O5 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 2 years |
CAS No. | 913376-84-8 |
Synonyms | SYN 1143,SYN-1143 |
SMILES | O=C(C1=C(C)N(CC(C)(O)C)N(C2=CC=CC=C2)C1=O)NC3=CC=C(OC4=CC=NC5=CC(OC)=CC=C45)C(F)=C3 |
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