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T-705 (Favipiravir)

促销

viral RNA polymerase 抑制剂

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产品目录号: A11590

库存状态:中国现货中国现货

产品名 目录号 价格 数量
T-705 (Favipiravir) 10mg A11590-10
¥ 1,400.00
T-705 (Favipiravir) 25mg A11590-25
¥ 2,800.00
T-705 (Favipiravir) 50mg A11590-50
¥ 5,000.00
T-705 (Favipiravir) 100mg A11590-100
¥ 7,800.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

T-705, a substituted pyrazine compound, has been found to exhibit potent anti-influenza virus activity in vitro and in vivo.

T-705 (Favipiravir)

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顾客使用 Adooq 产品发表的高质量科研文献
Adooq 顾客使用 T-705 (Favipiravir) 发表的文献 (6)
  • JE Comer, .et al. Filovirus Virulence in Interferon α/ β and γ Double Knockout Mice, and Treatment with Favipiravir, Viruses, 2019, Feb 3;11(2). pii: E137 PMID: 30717492
  • Ma J, .et al. Enhancing the antiviral potency of ER 汐-glucosidase inhibitor IHVR-19029 against hemorrhagic fever viruses in vitro and in vivo, Antiviral Res, 2018, Feb;150:112-122 PMID: 29253498
  • Ji-Ae Kim, .et al. Favipiravir and Ribavirin Inhibit Replication of Asian and African Strains of Zika Virus in Different Cell Models, Viruses, 2018, Feb; 10(2): 72 PMID: 29425176
  • Haejin Chun, .et al. Efficient antiviral co-delivery using polymersomes by controlling the surface density of cell-targeting groups for influenza A virus treatment, Polym Chem, 2018, 9: 2116-2123
  • Baz M, .et al. Combination Therapy with Oseltamivir and Favipiravir Delays Mortality but Does Not Prevent Oseltamivir Resistance in Immunodeficient Mice Infected with Pandemic A(H1N1) Influenza Virus, Viruses, 2018, Nov 3;10(11) PMID: 30400276
  • Sehee Park, .et al. Combination Effects of Peramivir and Favipiravir against Oseltamivir-Resistant 2009 Pandemic Influenza A(H1N1) Infection in Mice, PLoS One., 2014, 9(7): e101325 PMID: 24992479

Chemical Information

目录号 A11590
Mechanism of action Inhibitor
分子量 157.1
化学分子式 C5H4FN3O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 259793-96-9
Synonyms T705, T 705
SMILES code C1=C(N=C(C(=O)N1)C(=O)N)F
化学名称 6-Fluoro-3-hydroxy-2-pyrazinecarboxamide6-fluoro-3,4-dihydro-3-oxo-Pyrazinecarboxamide

生物活性

Description
T-705, a substituted pyrazine compound, has been found to exhibit potent anti-influenza virus activity in vitro and in vivo.
Targets
RNA-dependent RNA polymerase

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 63.65 mL 318.27 mL 636.54mL
0.5 mM 12.73 mL 63.65 mL 127.31 mL
1 mM 6.37 mL 31.83 mL 63.65 mL
5 mM 1.27 mL 6.37 mL 12.73 mL

*The above data is based on the productmolecular weight 157.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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