T0070907

目录号: A11588

PPAR-γ antagonist

T0070907 Chemical Structure

CAS NO. 313516-66-4

T0070907 was identified as a potent and selective PPARgamma antagonist. With an apparent binding affinity (concentration at 50% inhibition of [(3)H]rosiglitazone binding or IC(50)) of 1 nm, T0070907 covalently modifies PPARgamma on cysteine 313 in helix 3 of human PPARgamma2.

库存: 现货

规格 价格 数量
5 mg
¥ 400.00
10 mg
¥ 600.00
50 mg
¥ 1,600.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

T0070907 was identified as a potent and selective PPARgamma antagonist. With an apparent binding affinity (concentration at 50% inhibition of [(3)H]rosiglitazone binding or IC(50)) of 1 nm, T0070907 covalently modifies PPARgamma on cysteine 313 in helix 3 of human PPARgamma2.
Targets
PPARγ (Cell-free assay) PPARα (Cell-free assay) PPARδ (Cell-free assay)
1 nM0.85 μM1.8 μM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 36.02 mL 180.08 mL 360.15 mL
0.5 mM 7.2 mL 36.02 mL 72.03 mL
1 mM 3.6 mL 18.01 mL 36.02 mL
5 mM 0.72 mL 3.6 mL 7.2 mL

*The above data is based on the productmolecular weight 277.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A11588
MECHANISM OF ACTION Antagonist
M. Wt 277.66
Formula C12H8ClN3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 313516-66-4
Synonyms T 0070907
SMILES ClC1=CC=C([N+]([O-])=O)C=C1C(NC2=CC=NC=C2)=O

产品标签

产品标签

其他人对该产品使用了下列标签:

使用空格分隔标签。使用单引号(')标注词组。

Product Questions

Product Questions

No Questions
Keywords:购买 T0070907 | T0070907 供应商 | 订购 T0070907 | T0070907 价格 | T0070907 生产商 | 订单 T0070907 | T0070907 代理商 | 购买 313516-66-4| 313516-66-4 供应商 | 订购 313516-66-4 | 313516-66-4 价格 | 313516-66-4 生产商 | 订单 313516-66-4 | 313516-66-4 代理商|buy T0070907 | T0070907 Supplier | purchase T0070907 | T0070907 cost | T0070907 manufacturer | order T0070907 | T0070907 distributor | buy 313516-66-4| 313516-66-4 Supplier | purchase 313516-66-4 | 313516-66-4 cost | 313516-66-4 manufacturer | order 313516-66-4 | 313516-66-4 distributor
Rewards