T0070907

Name: T0070907
SKU: A11588
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A11588

PPAR-γ 拮抗剂

T0070907 被确认为一种强效且选择性的 PPARgamma 拮抗剂。其表观结合亲和力（50%抑制[(3)H]罗格列酮结合的浓度或 IC(50)）为1纳摩尔，T0070907 在人类 PPARgamma2 的螺旋3上的半胱氨酸313位点与 PPARgamma 形成共价修饰。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥315.00	现货
25mg	¥595.00	现货
50mg	¥1,015.00	现货
100mg	¥1,400.00	现货
200mg	¥1,820.00	现货
500mg	¥3,115.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

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生物活性

Discription

T0070907 was identified as a potent and selective PPARgamma antagonist. With an apparent binding affinity (concentration at 50% inhibition of [(3)H]rosiglitazone binding or IC(50)) of 1 nm, T0070907 covalently modifies PPARgamma on cysteine 313 in helix 3 of human PPARgamma2.

Targets

Target	Value

产品信息

目录号	A11588
分子式	C12H8ClN3O3
分子量	277.66
CAS号	313516-66-4
SMILES	ClC1=CC=C([N+]([O-])=O)C=C1C(NC2=CC=NC=C2)=O
其他名称	T 0070907
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	24 mg/mL (86.43 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+45% PEG 300+ddH2O	8 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	36.02 mL	180.08 mL	360.15 mL
0.5 mM	7.2 mL	36.02 mL	72.03 mL
1 mM	3.6 mL	18.01 mL	36.02 mL
5 mM	0.72 mL	3.6 mL	7.2 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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