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T0901317

促销

LXR/FXR 激动剂

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产品目录号: A12652

库存状态:中国现货中国现货

产品名 目录号 价格 数量
T0901317 10mg A12652-10
¥ 500.00
T0901317 25mg A12652-25
¥ 700.00
T0901317 50mg A12652-50
¥ 1,000.00
T0901317 100mg A12652-100
¥ 1,500.00
T0901317 10mM * 1mL in DMSO A12652-10mM-D
¥ 500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

T0901317 is a potent, high affinity liver X receptor (LXR) agonist (EC50 ~ 50 nM, Kd values are 7 and 22 nM for LXR-?? and LXR-?? respectively).

T0901317

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Chemical Information

目录号 A12652
Mechanism of action Agonist
分子量 481.33
化学分子式 C17H12F9NO3S
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 293754-55-9
Synonyms N/A
SMILES code C1=CC=C(C=C1)S(=O)(=O)N(CC(F)(F)F)C2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
化学名称 N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,?2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phe?nyl]benzenesulfonamide

生物活性

Description
T0901317 is a potent, high affinity liver X receptor (LXR) agonist (EC50 ~ 50 nM, Kd values are 7 and 22 nM for LXR-?? and LXR-?? respectively).
Targets
LXR FXR
50 nM(EC50)5 μM(EC50)

溶解性

Solubility (25°C)* In vitro DMSO 96 mg/mL (199.44 mM)
Water <1 mg/mL (<1 mM)
Ethanol 96 mg/mL (199.44 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.78 mL 103.88 mL 207.76mL
0.5 mM 4.16 mL 20.78 mL 41.55 mL
1 mM 2.08 mL 10.39 mL 20.78 mL
5 mM 0.42 mL 2.08 mL 4.16 mL

*The above data is based on the productmolecular weight 481.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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