Tacrine HCl Hydrate
目录号: A16970
AChE and BChE 抑制剂
盐酸他克林水合物是一种同时抑制乙酰胆碱酯酶(AChE)和丁酰胆碱酯酶(BChE)的抑制剂,其半抑制浓度(IC50)分别为31纳摩尔和25.6纳摩尔。
Discription | Tacrine hydrochloride hydrate is an inhibitor of both acetyl (AChE) and butyryl-cholinestrase (BChE) with IC50s of 31 nM and 25.6 nM, respectively. |
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目录号 | A16970 |
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分子式 | C13H17ClN2O |
分子量 | 252.74 |
CAS号 | 206658-92-6 |
SMILES | NC1=C(CCCC2)C2=NC3=CC=CC=C31.[H]Cl.O |
其他名称 | THA hydrochloride hydrate, Tetrahydroaminacrine hydrochloride hydrate |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 43 mg/mL | |
Water | 43 mg/mL | ||
Ethanol | 43 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 39.57 mL | 197.83 mL | 395.66 mL |
0.5 mM | 7.91 mL | 39.57 mL | 79.13 mL |
1 mM | 3.96 mL | 19.78 mL | 39.57 mL |
5 mM | 0.79 mL | 3.96 mL | 7.91 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2