Tacrine HCl
目录号: A17374
AChE & butyrylcholinesterase 抑制剂
Tacrine 是氨基吖啶的衍生物,它作为乙酰胆碱酯酶(AChE)和丁酰胆碱酯酶的抑制剂(IC50 分别为 31 和 26.5 nM)。
Discription | Tacrine is a derivative of aminoacridine that functions as an inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (IC50s = 31 and 26.5 nM, respectively). |
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目录号 | A17374 |
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分子式 | C13H15ClN2 |
分子量 | 234.73 |
CAS号 | 1684-40-8 |
SMILES | NC1=C(CCCC2)C2=NC3=CC=CC=C31.[H]Cl |
其他名称 | Hydroaminacrine; NSC72108; NSC-72108; NSC72108 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 44 mg/mL (187.45 mM) | |
Water | 44 mg/mL (187.45 mM) | ||
Ethanol | 44 mg/mL (187.45 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 42.6 mL | 213.01 mL | 426.02 mL |
0.5 mM | 8.52 mL | 42.6 mL | 85.2 mL |
1 mM | 4.26 mL | 21.3 mL | 42.6 mL |
5 mM | 0.85 mL | 4.26 mL | 8.52 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2