TAE684

目录号: A10662

ALK Inhibitor

TAE684 Chemical Structure

CAS NO. 761439-42-3

TAE684 is a inhibitor of ALK and also a potent inhibitor of LRRK2 kinase activity (IC(50) of 7.8nM against wild-type LRRK2, 6.1nM against the G2019S mutant).

库存: 现货

规格 价格 数量
5 mg
¥ 800.00
10 mg
¥ 1,200.00
50 mg
¥ 3,200.00
100 mg
¥ 4,500.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

TAE684 is a inhibitor of ALK and also a potent inhibitor of LRRK2 kinase activity (IC(50) of 7.8nM against wild-type LRRK2, 6.1nM against the G2019S mutant).
靶点信息
ALK (Cell-free assay)
3 nM
In vitro (25°C) DMSO 3 mg/mL (4.88 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol, pH 4 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.28 mL 81.41 mL 162.81 mL
0.5 mM 3.26 mL 16.28 mL 32.56 mL
1 mM 1.63 mL 8.14 mL 16.28 mL
5 mM 0.33 mL 1.63 mL 3.26 mL

*The above data is based on the productmolecular weight 614.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A10662
MECHANISM OF ACTION Inhibitor
M. Wt 614.2
Formula C30H40ClN7O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 761439-42-3
Synonyms NVP-TAE684 , TAE-684
SMILES CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC

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