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TAK-063

PDE10A 抑制剂?€?

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产品目录号: A15799

库存状态:中国现货中国现货

产品名 目录号 价格 数量
TAK-063 10mg A15799-10
¥ 900.00
TAK-063 25mg A15799-25
¥ 1,800.00
TAK-063 50mg A15799-50
¥ 2,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

TAK-063 is a highly potent, selective and orally active PDE10A inhibitor with IC50 of 0.30 nM; >15000-fold selectivity over other PDEs.

TAK-063

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Chemical Information

目录号 A15799
Mechanism of action Inhibitor
分子量 428.42
化学分子式 C23H17FN6O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 1238697-26-1
Synonyms TAK 063, TAK063
SMILES code COC1=CN(N=C(C1=O)C2=CC=NN2C3=CC=CC=C3)C4=C(C=C(C=C4)N5C=CC=N5)F
化学名称 1-(2-fluoro-4-pyrazol-1-ylphenyl)-5-methoxy-3-(2-phenylpyrazol-3-yl)pyridazin-4-one

生物活性

Description
TAK-063 is a highly potent, selective and orally active PDE10A inhibitor with IC50 of 0.30 nM; >15000-fold selectivity over other PDEs.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.34 mL 116.71 mL 233.42mL
0.5 mM 4.67 mL 23.34 mL 46.68 mL
1 mM 2.33 mL 11.67 mL 23.34 mL
5 mM 0.47 mL 2.33 mL 4.67 mL

*The above data is based on the productmolecular weight 428.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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