TAK-659 hydrochloride
目录号: A21885
Syk 抑制剂
TAK-659 盐酸盐是一种强效、选择性且可口服的脾脏酪氨酸激酶(Syk)抑制剂,其 IC50 为 3.2 nM。
Discription | TAK-659 hydrochloride is a potent, selective and orally available spleen tyrosine kinase (Syk) inhibitor with an IC50 of 3.2 nM. |
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目录号 | A21885 |
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分子式 | C17H22ClFN6O |
分子量 | 380.85 |
CAS号 | 1952251-28-3 |
SMILES | FC1=C(N[C@@H]2CCCC[C@@H]2N)N=C(C3=CN(C)N=C3)C4=C1CNC4=O.Cl |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Insoluble | |
Water | Warmed: 3 mg/mL (7.88 mM) | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 26.26 mL | 131.29 mL | 262.57 mL |
0.5 mM | 5.25 mL | 26.26 mL | 52.51 mL |
1 mM | 2.63 mL | 13.13 mL | 26.26 mL |
5 mM | 0.53 mL | 2.63 mL | 5.25 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2