TAK-659

目录号: A20450

SYK/FLT3 inhibitor

TAK-659

TAK-659 Chemical Structure

CAS NO. 1312691-33-0

TAK-659 is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively.

库存: 现货

规格 价格 数量
5 mg
¥ 1,260.00
10 mg
¥ 2,170.00
50 mg
¥ 6,440.00
100 mg
¥ 12,880.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

TAK-659 is a highly potent, selective, reversible and orally available dual inhibitor of spleen tyrosine kinase (SYK) and fms related tyrosine kinase 3 (FLT3), with an IC50 of 3.2 nM and 4.6 nM for SYK and FLT3, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.04 mL 145.18 mL 290.37 mL
0.5 mM 5.81 mL 29.04 mL 58.07 mL
1 mM 2.9 mL 14.52 mL 29.04 mL
5 mM 0.58 mL 2.9 mL 5.81 mL

*The above data is based on the productmolecular weight 344.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A20450
作用机制 Inhibitor (抑制剂)
M. Wt 344.39
Formula C17H21FN6O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1312691-33-0
Synonyms TAK659, TAK 659
SMILES FC1=C(N[C@@H]2CCCC[C@@H]2N)N=C(C3=CN(C)N=C3)C4=C1CNC4=O

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