TAK-733

目录号: A11040

MEK Inhibitor

TAK-733

TAK-733 Chemical Structure

CAS NO. 1035555-63-5

TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.

库存: 现货

规格 价格 数量
5 mg
¥ 900.00
10 mg
¥ 1,600.00
50 mg
¥ 4,500.00
100 mg
¥ 7,500.00
10mM * 1mL in DMSO
¥ 1,200.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

详情

TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
Targets
MEK1
3.2 nM
In vitro DMSO 101 mg/mL (200.3 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.83 mL 99.17 mL 198.33 mL
0.5 mM 3.97 mL 19.83 mL 39.67 mL
1 mM 1.98 mL 9.92 mL 19.83 mL
5 mM 0.4 mL 1.98 mL 3.97 mL

*The above data is based on the productmolecular weight 504.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

目录号 A11040
MECHANISM OF ACTION Inhibitor
M. Wt 504.2
Formula C17H15F2IN4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1035555-63-5
Synonyms TAK733
SMILES CN1C2=C(C(=C(C1=O)F)NC3=C(C=C(C=C3)I)F)C(=O)N(C=N2)C[C@H](CO)O

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