TAK-981
目录号: A20002
SUMO 抑制剂
TAK-981 是首个类别中的药物,是 SUMOylation 酶级联反应的选择性抑制剂,具有潜在的免疫激活和抗肿瘤活性。
| Discription | TAK-981 is a first in class and selective inhibitor of the SUMOylation enzymatic cascade, with potential immune-activating and antineoplastic activities. | |||||
|---|---|---|---|---|---|---|
| Cell Research |
|
| 目录号 | A20002 |
|---|---|
| 分子式 | C25H28ClN5O5S2 |
| 分子量 | 578.1 |
| CAS号 | 1858276-04-6 |
| SMILES | O=S(OC[C@@H]1[C@@H](O)C[C@H](NC2=NC=NC=C2C(C3=CC([C@@H]4NCCC5=C4C=C(Cl)C=C5)=C(C)S3)=O)C1)(N)=O |
| 其他名称 | TAK981, TAK 981 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 97 mg/mL (167.79 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.3 mL | 86.49 mL | 172.98 mL |
| 0.5 mM | 3.46 mL | 17.3 mL | 34.6 mL |
| 1 mM | 1.73 mL | 8.65 mL | 17.3 mL |
| 5 mM | 0.35 mL | 1.73 mL | 3.46 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2