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Talnetant hydrochloride

NK3 receptor 拮抗剂

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产品目录号: A15255

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Talnetant hydrochloride 10mg A15255-10
¥ 1,280.00
Talnetant hydrochloride 25mg A15255-25
¥ 2,800.00
Talnetant hydrochloride 50mg A15255-50
¥ 5,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Talnetant Hcl is a potent and selective NK3 receptor antagonist(ki=1.4 nM, hNK-3-CHO); 100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to 100 uM.

Talnetant hydrochloride

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Chemical Information

目录号 A15255
Mechanism of action Antagonist
分子量 418.92
化学分子式 C25H23ClN2O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 204519-66-4
Synonyms SB-223412 hydrochloride, SB223412 hydrochloride, SB 223412 hydrochloride, SB 223412-A
SMILES code CCC(C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)O.Cl
化学名称 3-hydroxy-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide;hydrochloride

生物活性

Description
Talnetant Hcl is a potent and selective NK3 receptor antagonist(ki=1.4 nM, hNK-3-CHO); 100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to 100 uM.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.87 mL 119.35 mL 238.71mL
0.5 mM 4.77 mL 23.87 mL 47.74 mL
1 mM 2.39 mL 11.94 mL 23.87 mL
5 mM 0.48 mL 2.39 mL 4.77 mL

*The above data is based on the productmolecular weight 418.92. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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