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Talnetant

NK3 receptor 拮抗剂

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产品目录号: A15254

库存状态:中国现货中国现货

产品名 目录号 价格 数量
Talnetant 10mg A15254-10
¥ 1,280.00
Talnetant 25mg A15254-25
¥ 2,800.00
Talnetant 50mg A15254-50
¥ 5,000.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

Talnetant is a potent and selective NK3 receptor antagonist(ki=1.4 nM, hNK-3-CHO); 100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to 100 uM.

Talnetant

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Chemical Information

目录号 A15254
Mechanism of action Antagonist
分子量 382.45
化学分子式 C25H22N2O2
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 174636-32-9
Synonyms SB-223412, SB223412, SB 223412
SMILES code CCC(C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)O
化学名称 3-hydroxy-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide

生物活性

Description
Talnetant is a potent and selective NK3 receptor antagonist(ki=1.4 nM, hNK-3-CHO); 100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to 100 uM.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.15 mL 130.74 mL 261.47mL
0.5 mM 5.23 mL 26.15 mL 52.29 mL
1 mM 2.61 mL 13.07 mL 26.15 mL
5 mM 0.52 mL 2.61 mL 5.23 mL

*The above data is based on the productmolecular weight 382.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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