Talquetamab (JNJ-64407564) is a humanized bispecific antibody engineered to target GPRC5D, a member of the G protein-coupled receptor family C group D, and CD3, a key component in T-cell activation. This antibody facilitates the recruitment and activation of T cells, leading to the selective killing of multiple myeloma (MM) cells expressing GPRC5D. Demonstrating significant antitumor activity, Talquetamab is pivotal in advancing therapeutic strategies for MM treatment through its dual targeting mechanism.
Talquetamab (JNJ-64407564) is a humanized bispecific antibody engineered to target GPRC5D, a member of the G protein-coupled receptor family C group D, and CD3, a key component in T-cell activation. This antibody facilitates the recruitment and activation of T cells, leading to the selective killing of multiple myeloma (MM) cells expressing GPRC5D. Demonstrating significant antitumor activity, Talquetamab is pivotal in advancing therapeutic strategies for MM treatment through its dual targeting mechanism.
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