Tamoxifen
目录号: A16738
selective estrogen receptor modulator (SERM)
Tamoxifen (ICI 47699) 是一种选择性雌激素受体调节剂(SERM),它可以阻断乳腺细胞中的雌激素作用,并在其他细胞中激活雌激素活性,如骨细胞、肝细胞和子宫细胞。
| Discription | Tamoxifen (ICI 47699) is a selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. | |||||
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| 目录号 | A16738 |
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| 分子式 | C26H29NO |
| 分子量 | 371.51 |
| CAS号 | 10540-29-1 |
| SMILES | CC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCN(C)C)C=C2)\C3=CC=CC=C3 |
| 其他名称 | ICI 47699; (Z)-Tamoxifen; trans-Tamoxifen |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro (25°C) | DMSO | 68 mg/mL (183.03 mM) | |
| Water | Insoluble | ||
| Ethanol | 68 mg/mL | ||
| In vivo | 2% DMSO+30% PEG 300+2% Tween 80+ddH2O | 1 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.92 mL | 134.59 mL | 269.17 mL |
| 0.5 mM | 5.38 mL | 26.92 mL | 53.83 mL |
| 1 mM | 2.69 mL | 13.46 mL | 26.92 mL |
| 5 mM | 0.54 mL | 2.69 mL | 5.38 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2