Tanezumab (RN-624) is a humanized monoclonal antibody that exhibits high affinity and specificity for nerve growth factor (NGF). By effectively blocking the interaction of NGF with its receptors, p75 and TrkA, Tanezumab modulates pain signaling pathways in the peripheral nervous system. This antibody is utilized extensively in research focused on both acute and chronic pain conditions, including osteoarthritis, knee pain, neuralgia, and post-herpetic neuralgia, providing a valuable tool for the study of pain mechanisms and therapeutic interventions.
Tanezumab (RN-624) is a humanized monoclonal antibody that exhibits high affinity and specificity for nerve growth factor (NGF). By effectively blocking the interaction of NGF with its receptors, p75 and TrkA, Tanezumab modulates pain signaling pathways in the peripheral nervous system. This antibody is utilized extensively in research focused on both acute and chronic pain conditions, including osteoarthritis, knee pain, neuralgia, and post-herpetic neuralgia, providing a valuable tool for the study of pain mechanisms and therapeutic interventions.
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