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TAPI-2

TACE/MMP 抑制剂

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产品目录号: A14009

库存状态:中国现货中国现货

产品名 目录号 价格 数量
TAPI-2 2mg A14009-2
¥ 1,800.00
TAPI-2 5mg A14009-5
¥ 4,000.00
TAPI-2 10mg A14009-10
¥ 7,500.00

产品仅用于研究,不针对患者销售,望谅解.

产品简介

TAPI-2 is an inhibitor of TACE, ADAMs, ACE secretase, and other MMPs (metalloproteinases). TAPI-2 blocks release of DCC7, APP, TNFα, L-selectin, NOTCH, TGFα, IL-6R9, erbB2/HER2, and ACE. This inhibitor has been used in tissue culture.

TAPI-2

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Chemical Information

目录号 A14009
Mechanism of action Inhibitor
分子量 415.53
化学分子式 C19H37N5O5
Solubility DMSO
纯度 >98%
储存方式 at -20°C 2 years
CAS No. 187034-31-7
Synonyms TNF Protease Inhibitor 2
SMILES code C[C@@H](C(=O)NCCN)NC(=O)[C@H](C(C)(C)C)NC(=O)C(CC(C)C)CC(=O)NO
化学名称 N-[2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide

生物活性

Description
TAPI-2 is an inhibitor of TACE, ADAMs, ACE secretase, and other MMPs (metalloproteinases). TAPI-2 blocks release of DCC7, APP, TNFα, L-selectin, NOTCH, TGFα, IL-6R9, erbB2/HER2, and ACE. This inhibitor has been used in tissue culture.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.07 mL 120.33 mL 240.66mL
0.5 mM 4.81 mL 24.07 mL 48.13 mL
1 mM 2.41 mL 12.03 mL 24.07 mL
5 mM 0.48 mL 2.41 mL 4.81 mL

*The above data is based on the productmolecular weight 415.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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