Tarextumab (OMP-59R5) is a fully human IgG2 monoclonal antibody designed to target and inhibit Notch2 and Notch3 receptors. This antibody exhibits potent anti-tumor activity by interfering with the Notch signaling pathway, which is often implicated in the regulation of cell differentiation, proliferation, and apoptosis. Tarextumab is primarily utilized in oncological research to explore therapeutic strategies against various cancers where Notch signaling plays a critical role.
Tarextumab (OMP-59R5) is a fully human IgG2 monoclonal antibody designed to target and inhibit Notch2 and Notch3 receptors. This antibody exhibits potent anti-tumor activity by interfering with the Notch signaling pathway, which is often implicated in the regulation of cell differentiation, proliferation, and apoptosis. Tarextumab is primarily utilized in oncological research to explore therapeutic strategies against various cancers where Notch signaling plays a critical role.
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