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Targapremir-210 is a potent miR-210 inhibitor with an IC50 of 200 nM in MDA-MB-231 cells. Targapremir-210 binds to the Dicer site of the miR-210 hairpin precursor. This interaction inhibits production of the mature miRNA.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 16.87 mL | 84.36 mL | 168.72 mL |
0.5 mM | 3.37 mL | 16.87 mL | 33.74 mL |
1 mM | 1.69 mL | 8.44 mL | 16.87 mL |
5 mM | 0.34 mL | 1.69 mL | 3.37 mL |
*The above data is based on the productmolecular weight 592.69. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A20886 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 592.69 |
Formula | C32H36N10O2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1049722-30-6 |
Synonyms | Targapremir210, Targapremir 210 |
SMILES | O=C(NCCCN=[N+]=[N-])CCCOC1=CC=CC(C2=NC3=CC=C(C4=NC5=CC=C(N6CCN(C)CC6)C=C5N4)C=C3N2)=C1 |
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