TAS4464

Name: TAS4464
SKU: A18485
Price: 1260 CNY
Rating: 5 (288 reviews)

目录号: A18485

NAE 抑制剂

TAS4464 是一种高效且选择性的 NEDD8 激活酶 (NAE) 抑制剂，其 IC50 为 0.955 nM。

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Grouped product items
规格	价格	库存
5mg	¥1,260.00	现货
10mg	¥2,100.00	现货
25mg	¥4,200.00	现货
50mg	¥7,700.00	现货
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Data Sheet

SDS

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生物活性

Discription	TAS4464 is a highly potent and selective inhibitor of NEDD8 activating enzyme (NAE), with an IC50 of 0.955 nM.

产品信息

目录号	A18485
分子式	C21H23FN6O6S
分子量	506.5
CAS号	1848959-10-3
SMILES	NC1=C2C(N([C@H]3[C@@H]([C@@H]([C@@H](CNS(=O)(N)=O)O3)O)O)C=C2C#CC4=C(F)C=CC=C4OCC)=NC=N1
其他名称	TAS4464; TAS-4464; TAS 4464
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	90 mg/mL (177.68 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.74 mL	98.72 mL	197.43 mL
0.5 mM	3.95 mL	19.74 mL	39.49 mL
1 mM	1.97 mL	9.87 mL	19.74 mL
5 mM	0.39 mL	1.97 mL	3.95 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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