Zipalertinib (TAS6417)

Name: Zipalertinib (TAS6417)
SKU: A19541
Price: 560 CNY
Rating: 5 (288 reviews)

目录号: A19541

EGFR 抑制剂

TAS6417 是一种 EGFR 抑制剂，对患有 NSCLC（非小细胞肺癌）的患者是一个有效的药物候选，其 IC50 值在 1.1-8.0 nM 范围内。

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Grouped product items
规格	价格	库存
1mg	¥560.00	现货
2mg	¥840.00	现货
5mg	¥1,330.00	现货
10mg	¥2,240.00	现货
25mg	¥4,585.00	现货
50mg	¥7,385.00	现货
100mg	¥11,375.00	现货
500mg	¥22,925.00	现货
*10mM 1mL in DMSO**	¥1,540.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

TAS6417 is an EGFR inhibitor and an efficacious drug candidate for patients with NSCLC, with IC50 values ranging from 1.1-8.0 nM.

Targets

Target	Value

产品信息

目录号	A19541
分子式	C23H20N6O
分子量	396.44
CAS号	1661854-97-2
SMILES	NC1=C2C(N3C(C(C)=C[C@@H](C3)NC(C=C)=O)=C2C4=CC5=CC=CC=C5N=C4)=NC=N1
其他名称	TAS 6417, TAS-6417
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	71 mg/mL (179.09 mM)
	Water	Insoluble
	Ethanol	71 mg/mL (179.09 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.22 mL	126.12 mL	252.24 mL
0.5 mM	5.04 mL	25.22 mL	50.45 mL
1 mM	2.52 mL	12.61 mL	25.22 mL
5 mM	0.5 mL	2.52 mL	5.04 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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