Tasquinimod
目录号: A12616
HDAC4 抑制剂
Tasquinimod 是一种口服活性抗血管生成剂，通过变构抑制 HDAC4 信号传导来发挥作用。
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生物活性
| Discription | Tasquinimod is an orally active antiangiogenic agent by allosterically inhibiting HDAC4 signalling. | ||
|---|---|---|---|
| Targets |
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产品信息
| 目录号 | A12616 |
|---|---|
| 分子式 | C20H17F3N2O4 |
| 分子量 | 406.36 |
| CAS号 | 254964-60-8 |
| SMILES | CN1C2=C(C(=CC=C2)OC)C(=C(C1=O)C(=O)N(C)C3=CC=C(C=C3)C(F)(F)F)O |
| 其他名称 | ABR-215050 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 78 mg/mL (191.95 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 11 mg/mL (27.06 mM) | ||
| In vivo | 5% DMSO+30% PEG 300+ddH2O | 7 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.61 mL | 123.04 mL | 246.09 mL |
| 0.5 mM | 4.92 mL | 24.61 mL | 49.22 mL |
| 1 mM | 2.46 mL | 12.3 mL | 24.61 mL |
| 5 mM | 0.49 mL | 2.46 mL | 4.92 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 254964-60-8 | 254964-60-8 供应商 | 254964-60-8 花费 | 254964-60-8 生产商 | 订购 254964-60-8 | 254964-60-8 代理商