TAT-cyclo-CLLFVY
目录号: A22796
TAT-cyclo-CLLFVY 是一种环状肽抑制剂,用于抑制 HIF-1 异源二聚体化,从而抑制癌细胞中的缺氧信号传导。TAT-cyclo-CLLFVY 通过破坏 HIF-1α/HIF-1β 蛋白-蛋白相互作用,具有 1.3 μM 的 IC50 值。
Discription | TAT-cyclo-CLLFVY is a cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. TAT-cyclo-CLLFVY disrupts HIF-1α/HIF-1β protein-protein interaction with an IC50 of 1.3 μM. |
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目录号 | A22796 |
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分子式 | C111H188N42O24S2 |
分子量 | 2559.08 |
CAS号 | 1446322-66-2 |
Sequence shortening | CGRKKRRQRRRPPQ.cyclo(CLLFVY) (Disulfide bridge:Cys1-Cys1') |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2